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Pre-implantation genetic diagnosis (PGD)

Genetic analysis on early embryos

Since 2014, it has been possible to test early embryos for serious genetic disorders using pre-implantation diagnosis (PGD) in Germany, following approval from the relevant ethics committee. However, only select fertility centres working with a genetic centre receive regulatory approval for this test. Both partners must meet the highest quality standards in their respective fields.

In 2014, the Fertility Center Hamburg was the first fertility clinic in Germany to obtain approval for PGD. As of Juliy 2020, we have been re-approved as a center for PGD and offer this service in cooperation with the "Medizinisch Genetisches Zentrum" in Munic (MGZ). Further information can be found here: PID-Zentrum München

With pre-implantation genetic diagnosis, we can help patients who carry an increased genetic risk of miscarriage/stillbirth or specific monogenic hereditary disorders. If you are interested in carrying out PGD, please send us an email with the assessment/findings of your illness, giving your name and contact details (address and telephone number) to our service team.

If you have any specific questions, please don’t hesitate to call us at +49 (0)40 30804-520, -521 or -424.

Treatment procedure

A minimum number of fertilised egg cells must develop properly for the method to be used successfully. On the fifth day of cell culture, a small sample can usually be taken from the cells and tested. These special genetic tests are sometimes very extensive and time-consuming, meaning that the embryos are generally frozen (vitrification) after cell sampling until the results are available. In a subsequent freeze-thaw cycle without hormonal stimulation, the suitable embryos are then implanted into the uterus. PGD is currently used in the following indications: translocations, numerical chromosome malsegregations or monogenic disorders.

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